Reinhold Zwintscher was called to be a traveling missionary in Manitoba in 1899 and also served Assiniboia in Saskatchewan, but spent a great deal of time in Immanuel, Winnipeg. He served the nearby congregation at Neudorf during a vacancy in 1899 as well. During his time at Immanuel he oversaw the growth of the congregation, the building of a new church and school and the achievement of self -supporting status by 1905. Zwintscher also assisted in the formation of a second Missouri Synod congregation in Winnipeg in 1904 called Holy Cross, and congregations at Winkler in 1901, at Tupper (Plumas) in 1903, and Poplar Point, Niverville, Plum Coulee and Portage la Prairie, Manitoba in subsequent years. His missions experienced aggressive competition for the German Lutherans from the Ohio Synod, especially in Winnipeg after 1905 and the Missouri Synod lost many congregants. Zwintscher accepted a call to the United States in 1910.